Interested to Learn About Spermidine, Clinical Health Benefits, Foods, and Supplements?

 

Who doesn’t want a more youthful look, better skin, less wrinkles, better cardiovascular function, stronger immunity, less inflammation, balanced mental health and a longer lifespan with ability?

Is it even possible that Nature has provided a compound that self-cleans your body’s cells, rejuvenates cellular functions and clears away damaged mitochondria?

It is my job to keep informed about dietary supplements as a certified supplement distributor from The Institute of Cellular Nutrition. So it was with keen interest that I was very interested to research a new word related to health; namely, Spermidine. Along the way I was mesmerized by a developing industry filled with new meanings that have added new perspectives to maintaining good health. In fact, based on what I read I took immediate action. The hope is that you will be curious enough to do some research, too. See links below.

What in the world is Spermidine?

It’s everywhere as a natural compound classified as a polyamine metabolite, meaning it has more than two primary amino groups in its structure that occur in all living organisms for various metaboloic functions. Its molecular structure is C7 H19 N3.

It is found in all plants and animals and in nearly every cell of your body with a unique property that was recently discovered by doctors in Austria.

What makes this discovery so currently exciting is the description of spermidine as a novel autophagy inducer and longevity elixir.

In other words, spermidine works as an anti-aging compound because its critical role is to regulate autophagy.

WHAT IS AUTOPHAGY?

Autophagy is the renewal or self-cleaning process by which the human body can break down and recycle unnecessary or damaged cell components.

Cell division and proliferation are important characteristics of living organisms based on a cell cycle responsible for cell growth, survival and death. Spermidine plays a role in modulating and sustaining normal cell cycles. Its concentration declines with age.

The fact is aging is the main risk factor in age-related diseases because our cells age as well. When they become old or damaged, this causes a build up of dead or toxic organelle matter in our bodies, potentially leading to age-related disease and injury.

Spermidine in our cells optimizes autophagy, sustains normal cell cycles for renewal to return to peak efficiency.

It removes toxic proteins from the cells that may be a cause of many age-related diseases like neurodegenerative, cardiovascular, immune and muscle-skeletal problems. Many studies have shown promising results and human translation is ongoing.

Several clinical benefits of spermidine have been researched and are attributed to many of these factors in how it works:

— suppresses free radicals and oxidative stress that reduces inflammation

— enhances cell growth by regulating the cellular lifecycle and preventing cell death

— maintains normal lipid metabolism and can protect cellular DNA from oxidative attacks

— decreases the development of atherosclerosis in mice by decreasing inflammation and improving cell (mitochondria) functioning

— prevents neurologic diseases by protecting against nerve damage in these areas of the brain

— decreases blood sugar levels and improves the body’s ability to use insulin

— reduces obesity in a study involving mice by increases autophagy in fat cells

— thought to boost the immune system against outside threats while preventing the immune system from attacking normal cells with increased ability to fight viruses like influenza

— increases bone strength and prevents age related bone loss and osteoporosis related skeletal muscle problems

I paid particular attention to spermidine actions on osteoarthritis that include acting as an antioxidant, anti-inflammatory, and an autophagy activator to preserve normal cartilage and help to degrade arthritic cartilage.

Ongoing research will definitely attest to these actions of spermidine to enhance longevity and promote a healthy lifespan.

Eat a diet rich in Spermidine

The best way to maximize spermidine is to eat a diet rich with polyamine foods that help to synthesize spermidine. It’s important to maintain optimal levels of spermidine throughout life to reduce the development of diseases and increase longevity. The foods highest in spermidine include:

Wheat and whole grains

Broccoli and cauliflower

Mushrooms

Peas

Mangos

Soybeans and soy products

Chicken

Spermidine as a supplement

However, it can be a challenge to consume enough spermidine through diet alone, which is where spermidine supplements come in. There are a host of companies already promoting their brands with two different kinds of supplements; some with synthetic spermidine while others contain spermidine from wheat germ extract.

Look for best qualifying factors:

— high quality organic source, free from cotaminants, avoid junk fillers

— based on latest research from a scientific advisory board

— produced in a facility with GMP standards

— third-party tested with a good reputation among users (testimonials)

— consider the dosage and form of the supplement…capsules, powders, or liquids

— adhere to the manufacturer’s instructions

— seek advice from a healthcare provider for more personalized recommendations before starting any new suplement regime.

Certainly, I did not hesitate to do some comparison shopping and ordering a Spermidine supplement because of my worries about osteoarthritis.

FINAL WORDS

In 2016, a research team at the University of Graz in Austria led by Dr. Frank Madeo discovered spermidine’s ability to trigger autophagy.

Since this revolutionary discovery, approximately 100 international research teams have been investigating this substance and its health benefits. The research is still in its early stage, in terms of scientific investigation, but there are few substances that are better and more intensively researched than spermidine with exciting results that could have major implications on our understanding of how living cells function and age.

As a human, aging is an irreversible and inevitable process faced soon enough with diverse age-related diseases. But early stages of scientic study have shown this natural compound has anti-aging effects from a Molecular Perspective with precise mechanisms still being studied.

The good news is that there are new insights into promising potential diagnostic and therapeutic applications of spermidine in aging and age-related diseases.

One thing is certain: science continues to confirm what Nature’s bounty of phytonutrients has always provided for a health body and life expectancy in a balanced environment. Nature’s nutraceutical bounty has always held the locks and keys that science is now unlocking. How fascinating!

Questions and comments are always appreciated.

Annemarie Berukoff

amarie10@gmail.com

250 304 9710 PST

PS: Request links to do your own research